THE DEVELOPMENT OF THE NEUROTOXICOLOGY'S INVESTIGATION

N.V. Kokshareva

The experimental data about mode of neurotoxic action of anticholinesterase pesticides and series of medicinal remedies were generalized in this work.

Electrophysiological analysis of organophosphorus compounds' and carbamates' mode of action on the functional state of central neurous system and peripheral nerve, nerve-muscular conduction in warm-blooded animals are presented in this report. The early manifestation and mechanism of delayed neurotoxicity induced by organophosphorus pesticides are discussed. Therapeutical efficacy of diethyxime and inductors of monooxigenase system in experimental anticholinesterase pesticides' intoxication were shown too.

article


| contents |