TOXICOLOGY OF PESTICIDES

THE PROCESS OF FREE RADICAL PEROXIDE OXIDIZATION OF LIPIDES IN THE MODE OF ACTION OF SYNTHETIC PYRETHROIDES

V.G.Bardov, Doctor of Medicine, Professor; O.B.Leonenko, Doctor of Biology;
S.T.Omelchuk, Candidate of Medicine; L.M.Sassinovich, Doctor of Medicine

In course of the study conducted on white rats it was established that synthetic pyrethroides (Danitol, Decis, Mavrik, Fastac, Cybolt) when applied one time or multiple times (2 and 6 months), break the process of the peroxide oxidization of lipides by initiating it. The changes in the speed of oxidization of lipides and antiradical activity were noted as well. The results of the study can be used for evaluating the harmful impact of pesticides belonging to the group of synthetic pyrethroids. This can help scientifically substantiate their save levels of application and rate fixing in the objects of environment.

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