THE MORPHO-FUNCTIONAL CHANGES IN THE HYPOTHALAMO-HYPOPHISEAL SYSTEM AFTER THE HERBICIDE 2,4-D AND PLANT GROWTH STIMULATOR IVIN ACTION

N.O. Karpezo, O.M. Gurniak, O.S. Matsuh, G.V. Ostrovska, V.K. Ribalchenko

The obtained data showed the marked differences in 2,4-D and ivin effect on hypothalamic magnocellular nucleus neurocytes. Thus, the paraventricular nucleus neurocytes are more susceptible to 2,4-D, where many cells with pyknotic nucleus appear. Whereas ivin cause disfunction of about half of supraoptic nuclei cells. Simultaneous action of 2,4-D and ivin enlarges the abnormalities induced either of the pesticides separately. Compensatory reactions are more evident in supraoptic nuclei.

The great majority of neurocytes, which preserve the normal nuclei structure and actively synsethize the neurosecretory material, remove the neurosecretory granules from the body cells. But pesticides, especially 2,4-D, slow down the later movement of the neurosecret along axons. Just the same time pesticides do not prevent the neurosecret secretion in the median eminence (neurohemal zona) and in neurohypophysis.

The obtained morpho-functional data showed the direct damaging action of pesticide and its influence on the function of hypothalamo-hypophyseal system.

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