BIOCHEMICAL ASPECTS OF DAMAGING ACTION OF ANTIDIABETIC MEDICAL AGENT — A SUCCINIC ACID DERIVATIVE

F.A. Kolodub, M.Yu. Kudrya, S.V. Ivanov, I.A. Palagina, N.V. Ustenko, N.V. Melnikovskaya, L.V. Mogilat, V.B. Lotskina

High sensitivity monooxigenasic system (MOS) microsomial fractions of a liver of rats under introduction phensuccinal in comparison with indexes of the common toxicity fixed. One of leading biochemical mechanisms of a potential toxicity phensuccinal is intensification of processes lipoperoxidation microsomal membranes owing to an activation еlectrontrasport chain of МОS.

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