HEPATOPROTECTIVE ACTION OF SODIUM SUCCINATE AT POISONING BY HERBICIDE 2,4-D

N.O. Karpezo, O.M. Gurniak, S.N. Tsyvinska, О.V. Linchak, V.K. Ribalchenko

Herbicide 2,4-D provoked hepatitis, vessels thrombosis, sinusoids constriction, hepatocytes nuclei decrease. The sodium succinate caused the hepatocytes activation and didn't influence on the sinusoids. Data analysis of the morpho-functional changes in liver after simultaneous action of 2,4-D and sodium succinate showed that the sodium succinate partly prevent injuries, provoked by 2,4-D.

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