THE ROLE OF METABOLIC ACTIVATION IN THE CHANGING DYNAMICS OF CYTOGENETIC DAMAGE INDUCTION IN MOUSE BONE MARROW CELLS WITH DIFFERENT MUTAGENS

S.E. Ogurtsova, A.M. Voitovich, K.G. Yeliseeva, V.D. Trusova, E.V. Krupnova, V.Yu. Afonin

Preliminary administration of xenobiotic metabolism inducers (b-naphthoflavone and t-butylhydroquinone) has resulted in changing the level of aberrant cells in fixation points which correspond to the maximum values of cytogenetic damages when administrating mutagens without inducers.

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