MEMBRANOSTABILIZING PROPERTIES OF PYRIDINECARBONIC ACID DERIVATIVE, COMPOUND PV-20, UNDER CONDITIONS OF RAT LIVER CELL CHEMICAL DAMAGE WITH TETRACHLOROMETHANE

Yu.I. Gubsky, N.V. Litvinova, A.G. Goriushko, V.F. Danilenko, A.N. Marchenko, T.N. Kurapova, N.M. Kurskaya, A.N. Velichko

Introduction of PV-20 compound to animals poisoned with tetrachloromethane normalizes intensity of lipid peroxidation reactions in liver cells endoplasmic reticulum membranes and results in partial or full correction of their structural and dynamic parameters that describe properties of surface and deep hydrophobic zones of microsomal membranes in the area of protein-lipid contact.

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