PROBLEM'S ARTICLES

TOXICODINAMIC OF IRRITATIVE SUBSTANCES

M.A. Mohort, O.Ye. Levchenko, N.M. Seredinska, L.M. Kirichok

In the review the modern data about toxicodinamic of irritative substances (IS) which are intended for using as special means by units of power departments and for self-defense is presented. The information about high elective and direct action of IS on membrane of sensory receptors is done. Indirect influence of IS on receptors is realized through releasing of endogenous chemical stimulators of pain. The reasons of pain sensation, mechanisms of development of motor, secretory effects, cardiovascular and respiratory violations are described. The attention is paid to possible long-term effects of IS using.

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