TREATMENT OF INTOXICATIONS

THE INFLUENCE OF HEMOGLOBINE PEPTIDE FRAGMENTS UPON THE PEROXIDATION IN BLOOD AT SATURNIUS INTOXICATION

T.N. Zaporozhets, O.I. Tsebrzhinsky

Guinea pigs who received lead acetatis (60 mg/kg per day) during 27 days had the increased processes of blood peroxidation and the decreased antioxidant defence The perioxide initiation is counected with the increase of methgemoglobine production and the superoxidedismutasa activity increase at catalasa activity decrease. The introduction of peptide complex (1 mg/kg per day during the last 7 days of intoxication) received by hemoglobine ferment hydrolysis promotes the normalizing neutrophile functional activity.

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