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TOXICOLOGY OF DRUGS TOXICOLOGYCAL CHARACTERISTIC OF A NEW DOMESTIC ANTIMYCOTIC ТЕОBОN-DITIOMYKOCID L.М. Sаsynоvitch, Yu.S. Каgаn, Е.А. Bаgley, N.М. Nеdоpitаnskа, N.А. Коrnutа, V.G. Коljadеnkо, V.I. Stеpаnеnkо, L.M. Shkaraputa, V.V. Dаnilеnkо, L.O. Тishchеnkо, V.М. Мjachin At the stage of preclinical tests it was established, that antimycotic Теоbоn-ditiomikocid is low toxic for laboratory animals over usage in organism by various paths. A skin and mucous membranes does not irritate, not allergic. The remote ef-fects of a course (mutagenic, cancerogenic, teratogenic, embryotoxic, recollection toxic) are not detected. Obtained results are recommended to extrapolate on the human. |