THE INFLUENCE OF SILIBORUM IN COMBINATION WITH A-TOCOPHEROL ACETATE ON TOXICOKINETIKS IN CONDITIONS OF AN ACUTE INTOXICATION

V.D. Lukianchuk, D.S. Kravets

Influencing means of medicinal preventive maintenance of venenatings dinitroortocresole (DNOK) — combination of siliborum and acetate of an a-tocopherol on nature of change toxicokinetics parameters have been studied.

Is rotined, that the given speed key of preventive means decelerates also quantity of entry of a pesticide in an organism, augments affinity to it of serumal proteins, reduces entry of this toxic agent in organs and tissues, and also augments its ascent with a urine and chole, that promotes fastest "refinement" of an organism from this xenobiotic and decrease of toxic effects, caused by it.

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