PROBLEM'S ARTICLES

XANTHINE OXIDASE AS THE COMPONENT OF THE SYSTEM FOR GEN-ERATION OF ACTIVE OXYGEN SPECIES

V.V. Sumbayev, A.Ya. Rozanov

The modern literary data devoted to the xanthine oxidase structure, mecha-nisms of action, regulation, and also substrate specificity as well as localisation of these enzyme in animal tissues are presented. The role of xanthine oxidase as the system for generation of reactive oxygen species in free radical peroxidation, can-cerogenesis and apoptosis was discussed.

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