THE TOXICOLOGICAL CHARACTERISTIC OF A NEW UKRAINIAN HYPOLIPIDEMIC DRUG UFIBRATE

V.A. Tumanov, S.A. Oliynik, M.A. Orinchak,
V.N. Serediuk, N.R. Muzikantova, N.A. Gorchakova

The primary toxicological characteristic of a new Ukrainian hypolipidemic drug — ufibrate — is given. By researches of acute toxicity of a drug on white mice, rats and cats is established, that it concerns to low-toxic substances. By long (6-month's) researches is established, that ufibrate in conditional-therapeutical and in conditional-toxic dozes did not cause changes a picture of blood at rabbits and rats. The clinical supervision which have been carried out on the patients with ischaemic disease of heart, have confirmed non-toxic characteristic of a drug. So, after treatment (reception of ufibrate tablets on 0,05 g three times per day after meal within 30 days) were not marked changes of a picture of blood and collateral reactions (including allergic).

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