TREATMENT OF INTOXICATIONS

ANTIOXIDANT PROTECTIVE SYSTEM SYSTEM ACTIVITY IN CONDITIONS OF CHRONIC RECEIPT OF DIETHYLDITIOCARBAMATE AT DIFFERENT LEVELS OF ANTIOXIDANT PROVISION

G.Yu.Ostrovskaya, V.N. Bobyrev

The results of the evaluation of antioxidant protective system activity in conditions of chronic input of diethylditiocarbamate - the inhibitor of cooper-containing oxydase at different levels of antioxidant provision are given in this work. It is established that an introduction of diethylditiocarbamate causes an induction of the free radical peroxide oxidation of lipids on the background of the decrease of antioxidant ferment activity, it being more vivid in the conditionis of alimentary antioxidants' deficit. The results achieved determine the perspectiveness of using of antioxidants as the means of preventing the toxic influence of diethylditiocarbamate and chemical products synthesized on its basis upon the organism.

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