MECHANISMS OF INTOXICATIONS

APPLIED ASPECTS OF PRION PROBLEM. II. TOXIC INITIATION OF SPONGIFORM ENCEPHALOPATHIES

S.V. Avilov, S.V. Verevka

The problems created by the possibility of non-prion initiation of spongiform encephalopathies as a consequence of malfunction of cellular folding with subsequent membrane folding of prion protein into the pathogenic conformation are discussed.

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