PESTICEDES REPRODUCTIVE TOXICITY RISK ASSESSMENT

N.R. Shepelskaya

The modern concept, main principles and the methodology of pesticides reproductive toxicity risk assessment are set forth. It is shown that risk assessment is the process by which scientific judgments are made concerning the potential for toxicity to occur in humans.

The basic components of risk assessment process are described: hazard identification, dose-response assessment, human exposure assessment, risk characterization.

The expediency of improvement of the extrapolation methodology and scientific substantiation of Reference Dose (RfD) and Reference Concentration (RfC) is emphasized.

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